— suspensions Download as a PDF or view online for free 11 In flocculated system the individual particle are contact with each other to form loose aggregate & create network like structure Rate of sedimentation is high Sediment is loosely packed When shaking it can be redisperse easily & reform the original suspension Flocculated
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— Pharmaceutical Suspension Free download as Powerpoint Presentation ppt PDF File pdf Text File txt or view presentation slides online 1 The document discusses pharmaceutical suspensions which are dispersions of an insoluble solid in a liquid medium 2 Suspensions are classified based on factors like the proportion of solid
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— administration The following presentations are typically used injectable solution a drug dissolved in water or other solvent that may include additives known as excipients to help stabilize it injectable suspension drug crystals are not soluble in water so the surface of the
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An oral pharmaceutical suspension has been one of the most favorable dosage forms for pediatric and geriatric patients or patients unable to tolerate solid dosage forms The liquid form is preferred because of the ease of swallowing and flexibility in the administration of doses This emerging area of suspensions as applied to the
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— The suspension dosage form has long been used for poorly soluble active ingre ents for various therapeutic indications Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts A good understanding of the fundamentals of disperse systems is essential in the development of
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— Pharmaceutical suspension Quality Control of Suspensions The following tests are carried out in the final quality control of suspension Appearance Color odor and taste Physical characteristics such as particle size determination and microscopic photography for crystal growth Sedimentation rate and Zeta Potential measurement
— Pharmaceutical suspension describes a dispersion of a solid material the dispersed phase in a liquid the continuous phase without reference to the particle size of the solid material However the particle size of the solid material can affect both its physicochemical behaviour of suspensions Because of this a distinction is usually made
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— An antimicrobial agent is a natural or synthetic substance that interferes with the growth and activities of microorganisms that may accidentally contaminate pharmaceutical dosage forms Pharmaceutical suspensions with water as the continuous phase are susceptible to microbial spoilage The source of the microbial growth may be
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— A disperse system is defined as a two phase system in which an insoluble or immiscible dispersed phase solid particles or liquid droplets is distributed through a continuous phase Disperse systems are typically classified based upon the size of the dispersed phase particles or droplets a Colloidal dispersions are generally
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— Desired features in a pharmaceutical suspension 5 The suspension should pour easily and evenly from the container 6 The formulation should be aesthetically pleasing to the eye nose and mouth The appearance viscosity texture and any other properties detected by the senses must be considered Available Suspension
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— Definition of a Pharmaceutical Suspending Agent Pharmaceutical suspending agents are a class of excipients added to disperse systems to ensure that any solid particles in the formulation are kept uniformly distributed within the continuous phase thereby maintaining physical stability of the Pharmaceutical dispersions include
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— Most pharmaceutical suspensions consist of an aqueous dispersion medium although organic or oily liquids are also used in some instances The discussion in this chapter is limited to solid liquid suspensions in aqueous medium A pharmaceutical suspension is a coarse dispersion of insoluble solid particles in a liquid medium
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— This presentation will explains the complete view on pharmacy & pharmaceutics in pharmacy A pharmaceutical suspension is a heterogeneous system in which finely divided solid particles
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— where V is the terminal velocity of sedimentation cm/s d is the diameter of the particle cm ρ 1 and ρ 2 are the densities of the suspended particles and the medium respectively g is the acceleration due to gravity and η 0 is the viscosity of the Important Considerations in Formulation of Suspension Formulation of a
— Properties of a good pharmaceutical suspension There is ready redispersion of any sediment produced on storage After gentle shaking the medicament stays in suspension long enough for a dose to be accurately measured The suspension is pourable Particles in suspension are small and relatively uniform
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— Many medicines in routine use are particulate suspensions of an active pharmaceutical ingredient in a continuous liquid phase Homogeneous dispersion of the key ingredient in such products is essential for uniform dosing Understanding and controlling suspension instability is therefore crucial to ensure that a product is both efficacious and
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— other elements into the pharmaceutical product 3 Leaching of container ingredients into the drug 4 Adsorption of the active drug or excipients by the plastic Effect of packaging material Metals • Various alloys and aluminiumtubes may be utilized as containers for emulsions ointments creams and
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2 — 7 Pharmaceutical suspension offers resistance to degradation of drugs due to hydrolysis oxidation or microbial activity 8 Duration and onset of action can be controlled Protamine Zinc Insulin suspension 9 When compared to solution dosage forms relatively higher concentration of drugs can be incorporated into suspension products
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— Pharmaceutical suspension is used for a variety of pharmaceutical uses for instance drugs having low solubility prednisolone are formulated as suspensions [3] Furthermore the degradation of some drugs oxytetracycline might be prevented when they are formulated as suspension [1] Suspension can
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— 1 Introduction A solid in liquid suspension is usually defined as a heterogeneous mixture system consisting of solid particles dispersed throughout a continuous liquid phase Babick 2016 Mewis and Wagner 2012 A significant number of active pharmaceutical ingredients are insoluble in solvents used for drug delivery to
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